化学与分子科学学院
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彭玲
出生年月:1966年9月
学历与职称:武汉大学珞珈讲座教授,法国国家科学研究中心终生研究员
专业方向:生物有机化学,化学生物学
电话:027 68754877or 68756225
Email: ling.peng@univmed.fr
教育与研究经历

1986,南京大学化学系,获学士学位

 1993,瑞士苏黎世高等理工学院, 博士学位

 1993,法国国家科学研究中心助理研究员,法国斯特拉斯堡路易巴斯德大学药学系

1997,法国国家科学研究中心研究员,法国斯特拉斯堡路易巴斯德大学药学系

1999,法国国家科学研究中心终生研究员,法国马赛地中海大学化学系

2000, 教育部长江学者,武汉大学特聘教授

2003, 武汉大学珞珈讲座教授

研究领域与兴趣

1.生物分子探针2.核酸及药物的传输;3.三唑核苷药物化学

教学情况
承担项目与课题
学术兼职
代表性成果

1. Zoltan Herincs, Krittalak Chakrabandhu, Britta Dost, Ling Peng, Fabien Conchonaud, Didier Marguet, Hai-Tao He, Anne-Odile Hueber, "Palmitoylation is Required for Fas to Trigger Cell Death Signaling", EMBO J. 2007, 26, 209-220.

2. Yi Xia,Wei Li, Fanqi Qu, Zhijin Fan, Xiufeng Liu, Charles Berro, Evelyne Rauzy, Ling Peng, "Synthesis of Bitriazolyl Nucleosides and Unexpectedly Different Reactivity of Azidotriazole Nucleoside Isomers in Huisgen Reaction", Org. Biomol. Chem. 2007, 5, 1695-1701.

3. Xin-Cheng Shen, Jiehua Zhou, Xiaoxuan Liu, Jiangyu Wu, Fanqi Qu, Zhi-Ling Zhang, Dai-Wen Pang, Gilles Quéléver, Cheng-Cai Zhang, Ling Peng, "Importance of Size to Charge Ratio in Construction of Stable and Uniform Nanoscale RNA/dendrimer Complexes", Org. Biomol. Chem. 2007, 5, 3674 – 3681.

4. Jiehua Zhou, Jiangyu Wu, Nadia Hafdi, Jean-Paul Behr, Patrick Erbacher, Ling Peng, "PAMAM Dendrimers for Efficient siRNA Delivery and Potent Gene Silencing", Chem. Commun. 2006, 2362-2364. (Highlighted hotpaper)

5. Han Chen, SophieLaurent, Sylvie Bedu,Fabio Ziarelli,Haili Chen, Yong Cheng, Cheng-Cai Zhang, Ling Peng, "Studying the Signaling Role of 2-Oxoglutaric Acid, by Using Analogues that Mimic the Ketone and Ketal Forms of 2-Oxoglutaric Acid", Chem. & Biol. 2006, 13, 849-856.

6. Jiehua Zhou, Jiangyu Wu, Xiaoxuan Liu, Fanqi Qu, Mu Xiao, Yi Zhang, Laurence Charles, Cheng-Cai Zhang, Ling Peng, "Cooperative Binding and Self-Assembling Behavior of Cationic Low-Molecular-Weight Dendrons with RNA Molecules", Org. Biomol. Chem. 2006, 4, 581 - 585.

7. Jiangyu Wu, Jiehua Zhou, Fanqi Qu, Benhui Bao, Yi Zhang, Ling Peng, "Polycationic dendrimers interact with RNA molecules: Polyamine dendrimers inhibit the catalytic activity of Candida ribozyme", Chem. Comm. 2005, 313-315. (Inside Cover)

8. SophieLaurent, Han Chen, Sylvie Bedu,Fabio Ziarelli,Ling Peng, Cheng-Cai Zhang, "A non-metabolizable analogue of the Krebs-cycle intermediate 2-oxoglutarate elicits heterocyst differentiation under repressive conditions in Anabaena sp. strain PCC 7120", Proc. Natl. Acad. Sci. U.S.A. 2005, 102, 9907-9912. (Cover Story)

9. Alexandre Specht, Philippe Bernard, Maurice Goeldner, Ling Peng "Mutually Induced Formation of Host-guest Complexes between p-Sulfonated Calix[8]arene and Photolabile Cholinergic Ligands", Angew. Chem. Int. Ed. Engl 2002, 41, 4706-4708.

获奖与荣誉
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